| RefNo | EC/2022/48 |
| Level | Item |
| Title | Vinuesa de la Concha, Maria Carola Garcia de: certificate of election to the Royal Society |
| Date | 21 April 2022 |
| Description | Certificate endorsing election of Carola Vinuesa as a Fellow of the Royal Society. Includes personal details of the elected Fellow, citation giving the reasons for election, and names of proposers. Signed by the Executive Director of the Royal Society, Julie Maxton. |
| Citation | Carola Vinuesa has defined how antibody production by B-cells is initiated by a novel T cell subset, follicular T helper cells (Tfh), characterised by the transcription factor Bcl6 and dependent on the cytokine IL-21. Her work established that increased Tfh activity causes autoimmunity and she discovered T follicular regulatory cells (Tfr) which regulate excessive antibody responses and prevent switching to allergenic IgE responses. Her recent discovery showing that Tfr produce the neuropeptide neuritin that prevents autoantibody production and IgE-mediated anaphylaxis paves the way for novel therapies in the control of antibody-mediated diseases. |
| Extent | 4p |
| Format | Computer printout |
| PhysicalDescription | A4 papers |
| AccessStatus | Closed |
| AccessConditions | Election certificates are subject to 50 year closure period from date of election. Details of proposers and date certificate was first submitted for candidacy are kept confidential until the 50 year closure period has elapsed. |