Record

RefNoJHG/2/17
Previous numbersJG/3/11B
LevelItem
TitleLaboratory notebook of John Henry Gaddum
Date1942-1953
Description'Edinburgh notebook' with details of experiments and demonstrations. Contains notes on a talks with Burn, Levvy (pages 7-9), experiments with MacDonald at Porton on pressure impinger (page 11), a list of pharmacologists (page 12), meeting agendas, removal of the [superior cervical ganglia] from a cat (pages 15-16), notes on two sick military personnel (page 22), Cu264 in chocolate and notes on accidental self-exposure (page 23), notes on histamine absorption (page 25), assays with histamine after filtering with charcoal (page 27), experiments with blood vessel dilation in a rabbit's ear (page 34-38), tests with adrenaline and histamine (pages 40-41), notes on reflex (page 42), filtration with Fuller's earth (pages 51-55), electrolysis, preparation of alumina in histamine solution (page 60), histamine added to urine (page 61), magnesium trisilicate and ammonia (page 62), pressure in blisters (pages 63, 75-76), adsorption of histamine on zinc (pages 63-65), experiments on volume of femoral artery (pages 67-70), tests with methylene blue (page 81), diagram of new electrodialysis apparatus (page 88), methods of blood collection (page 91-92), various cat perfusions (pages 96-106, 111-113), notes on a tumour extract (page 116), notes on statistics (page 120), superfusion of guinea pig's ileum for histamine (pages 123, 133), test of plethysmograph (page 130), assay for blood plasma before and during infusion of histamine (page 139), chromatography of serotonin (page 151), preparation of enteramine (page 159), experiments with addition of tryptamine (pages 159-162), notes on preparation of substance P by U S V Euler (page 163), chromatography of extracts (page 164), notes on theory of drug antagonism (page169), double superfusions with various liberations (pages 178-179), rat perfusions with Tyrode (page 185)

Report by Gaddum on 'Toxic Effects of Tartrates' (between pages 45-46).
Offprint of Gaddum article 'Tryptamine Receptors' from the Journal of Physiology, 1953, Vol. 119, demonstrating that HT and tryptamine act on the same receptors in guinea-pig's ileum (between pages 157-158).

Memo on staff meetings for the Pharmacology department (between cover and first page).
Ballot for the Pharmacological Society with notes for possible new members on back (between pages 13-14).
Annual balance sheet of the Physiological Society (between pages 46-47).
Extract from an article 'Penicillin Production Controlled,' describing ways of testing for pyrogenic substances.
Letter from C Williams from Rothamsted experimental station and draft of Gaddum's reply (between pages 94-95).

Diagram of a perfusion apparatus (p104).
Diagram of a dog's cerebrum (p169).
Diagram of an apparatus for recording small pressure changes (p192).
Diagram of a Constant Flow Chamber (between last page and cover).

Typescript notes on preparation of adrenochrome (p119).
University of Edinburgh degree form with notes on substance P and gut extracts (p155).
Notes on collection of plasma for the estimation of adrenaline (between last page and cover).
Notes on chromatography of serotonin-creatinine sulfate (p173).
Note from Nan Drummond confirming donation of two subject's blood for preparation of dried plasma (p189-190).
Extent1 volume
AccessStatusOpen
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